Future therapy of portal hypertension in liver cirrhosis – a guess
                    
                        
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منابع مشابه
Future therapy of portal hypertension in liver cirrhosis – a guess
In patients with chronic liver disease, portal hypertension is driven by progressive fibrosis and intrahepatic vasoconstriction. Interruption of the initiating and perpetuating etiology-mostly leading to necroinflammation-is possible for several underlying causes, such as autoimmune hepatitis, hepatitis B virus (HBV) infection, and most recently hepatitis C virus (HCV) infection. Thus, in the l...
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INTRODUCTION As the expected survival improves in individuals with the cystic fibrosis (CF), so they may be faced with a number of medical complications. OBJECTIVE The aim of this study was to analyze the prevalence of liver cirrhosis in our CF population as well as the clinical and genetic characteristics of these patients. METHODS All patients older than 2 years (n = 96) were screened for...
متن کاملAmiloride reduces portal hypertension in rat liver cirrhosis.
OBJECTIVE This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells. METHODS Liver cirrhosis in rats was induced by bile duct ligation (BDL) or thioacetamide (TAA) administration. The effects of zymosan for Kupffer cell (KC) activation or a thromboxane (TX) analogue (U46619) were test...
متن کاملContemporary concepts of the medical therapy of portal hypertension under liver cirrhosis.
Severe complications of liver cirrhosis are mostly related to portal hypertension. At the base of the pathogenesis of portal hypertension is the increase in hepatic vascular resistance to portal blood flow with subsequent development of hyperdynamic circulation, which, despite of the formation of collateral circulation, promotes progression of portal hypertension. An important role in its patho...
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Fast-track (FT) rehabilitation has proved to be successful in enhancing postoperative recovery, shorting hospital stay and reducing postoperative complications. This study aimed to evaluate the efficacy of FT rehabilitation protocol by a prospective study on liver cirrhosis patients with portal hypertension after surgical therapy. Pericardial vascular amputation and splenectomy surgery were per...
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ژورنال
عنوان ژورنال: F1000Prime Reports
سال: 2014
ISSN: 2051-7599
DOI: 10.12703/p6-95